Abstract
Geotrichum capitatum is a rare fungal pathogen that has infrequently affected immunocompromised patients with onco-hematologic diseases. Geotrichum capitatum invasive infection has been associated with poor prognosis, with a mortality rate ranging from 50% to 90%. Here, we report the first case of Geotrichum capitatum invasive fungal infection in a liver transplant recipient from an unrelated deceased donor, who was effectively treated with amphotericin B and voriconazole. We also reviewed the available literature in the field.
MeSH terms
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Amphotericin B / therapeutic use
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Antifungal Agents / therapeutic use
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Fatal Outcome
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Humans
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Immunocompromised Host
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Immunosuppressive Agents / adverse effects
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Invasive Fungal Infections / diagnosis
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Invasive Fungal Infections / drug therapy
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Invasive Fungal Infections / microbiology*
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Liver Transplantation / adverse effects*
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Male
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Middle Aged
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Multiple Organ Failure / etiology
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Opportunistic Infections / diagnosis
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Opportunistic Infections / drug therapy
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Opportunistic Infections / microbiology*
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Saccharomycetales / drug effects
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Saccharomycetales / pathogenicity*
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Sepsis / complications
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Sepsis / immunology
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Sepsis / microbiology
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Treatment Outcome
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Voriconazole / therapeutic use
Substances
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Antifungal Agents
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Immunosuppressive Agents
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Amphotericin B
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Voriconazole