Clinical multi-functional OCT for retinal imaging

Shinnosuke Azuma; Shuichi Makita; Deepa Kasaragod; Satoshi Sugiyama; Masahiro Miura; Yoshiaki Yasuno

doi:10.1364/BOE.10.005724

Clinical multi-functional OCT for retinal imaging

Biomed Opt Express. 2019 Oct 14;10(11):5724-5743. doi: 10.1364/BOE.10.005724. eCollection 2019 Nov 1.

Authors

Shinnosuke Azuma^{1

2}, Shuichi Makita^{1

2}, Deepa Kasaragod^{1

2}, Satoshi Sugiyama³, Masahiro Miura^{4

2}, Yoshiaki Yasuno^{1

2}

Affiliations

¹ Computational Optics Group, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8573, Japan.
² Computational Optics and Ophthalmology Group, Tsukuba, Ibaraki 305-8531, Japan.
³ Tomey Corporation, Nagoya, Aichi 451-0051, Japan.
⁴ Tokyo Medical University Ibaraki Medical Center, 3-20-1 Chuo, Ami, Ibaraki 300-0395, Japan.

Abstract

A compact clinical prototype multi-functional optical coherence tomography (OCT) device for the posterior human eye has been developed. This compact Jones-matrix OCT (JM-OCT) device integrates all components into a single package. Multiple image functions, i.e., scattering intensity, OCT angiography, and the degree of polarization uniformity, are obtained. The device has the capability for measuring local birefringence. Multi-functional imaging of several eyes with age-related macular degeneration is demonstrated. The compact JM-OCT device will be useful for the in vivo non-invasive investigation of abnormal tissues.