Current Advances in the Synthesis of Valuable Dipyrromethane Scaffolds: Classic and New Methods

Bruno F O Nascimento; Susana M M Lopes; Marta Pineiro; Teresa M V D Pinho E Melo

doi:10.3390/molecules24234348

Current Advances in the Synthesis of Valuable Dipyrromethane Scaffolds: Classic and New Methods

Molecules. 2019 Nov 28;24(23):4348. doi: 10.3390/molecules24234348.

Authors

Bruno F O Nascimento¹, Susana M M Lopes¹, Marta Pineiro¹, Teresa M V D Pinho E Melo¹

Affiliation

¹ CQC and Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal.

Abstract

This review presents the most recent developments on the synthesis of dipyrromethanes, covering classical synthetic strategies, using acid catalyzed condensation of pyrroles and aldehydes or ketones, and recent breakthroughs which allow the synthesis of these type of heterocycles with new substitution patterns.

Keywords: BODIPY; dipyrromethanes; dipyrromethenes; dipyrryl; pyrrolic macrocycles.

Publication types

Review

MeSH terms

Aldehydes / chemistry
Catalysis
Chemistry Techniques, Synthetic
Hydrochloric Acid
Indium / chemistry
Molecular Structure
Pyrroles / chemical synthesis*
Pyrroles / chemistry

Substances

Aldehydes
Pyrroles
dipyrromethane
Indium
indium trichloride
Hydrochloric Acid

Abstract

Publication types

MeSH terms

Substances

Grants and funding