Switching to a "turn-on" fluorescent probe for selective monitoring of cyanide in food samples and living systems

Hai Wu; Miaomiao Chen; Qinqin Xu; Ying Zhang; Pingping Liu; Wenyong Li; Suhua Fan

doi:10.1039/c9cc07492a

Switching to a "turn-on" fluorescent probe for selective monitoring of cyanide in food samples and living systems

Chem Commun (Camb). 2019 Dec 12;55(100):15137-15140. doi: 10.1039/c9cc07492a.

Authors

Hai Wu¹, Miaomiao Chen, Qinqin Xu, Ying Zhang, Pingping Liu, Wenyong Li, Suhua Fan

Affiliation

¹ School of Chemistry and Materials Engineering, Fuyang Normal University, Fuyang, Anhui 236037, P. R. China. wuhai317@126.com fansuhua@fudan.edu.cn.

PMID: 31789333
DOI: 10.1039/c9cc07492a

Abstract

A fluorescent probe (TPA-BTD-MT) was designed to monitor cyanide ions (CN-) with a "turn-on" response, changing from "turn-off" behavior due to the structural change. TPA-BTD-MT exhibited high selectivity for sensing CN- in several food samples and was successfully used for imaging CN- in living cells and animals with strong "turn-on" fluorescence.

MeSH terms

Aniline Compounds / chemistry
Animals
Cell Line, Tumor
Cyanides / analysis*
Fluorescent Dyes / chemistry*
Food Analysis / methods*
Limit of Detection
Manihot / chemistry
Manihot / metabolism
Mice
Mice, Inbred BALB C
Microscopy, Fluorescence
Optical Imaging*
Quantum Theory
Solanum tuberosum / chemistry
Solanum tuberosum / metabolism

Substances

Aniline Compounds
Cyanides
Fluorescent Dyes