The role of contrast-enhanced ultrasound in neurosurgical disease

Neurosurg Focus. 2019 Dec 1;47(6):E8. doi: 10.3171/2019.9.FOCUS19624.

Abstract

Contrast-enhanced ultrasound (CEUS) is a relatively new imaging modality in the realm of neurosurgical disease. CEUS permits the examination of blood flow through arteries, veins, and capillaries via intravascular contrast agents and allows vascular architectural mapping with extreme sensitivity and specificity. While it has established utility in other organ systems such as the liver and kidneys, CEUS has not been studied extensively in the brain. This report presents a review of the literature on the neurosurgical applications of CEUS and provides an outline of the imaging modality's role in the diagnosis, evaluation, and treatment of neurosurgical disease.

Keywords: AVM = arteriovenous malformation; CEUS = contrast-enhanced ultrasound; DAVF = dural arteriovenous fistula; EFSUMB = European Federation of Societies for Ultrasound in Medicine and Biology; GBM = glioblastoma; contrast-enhanced ultrasound; imaging; neurosurgery.

Publication types

  • Review

MeSH terms

  • Brain Diseases / diagnostic imaging*
  • Brain Diseases / surgery
  • Brain Neoplasms / diagnostic imaging
  • Brain Neoplasms / surgery
  • Carotid Artery Diseases / diagnostic imaging
  • Carotid Artery Diseases / surgery
  • Cerebrovascular Disorders / diagnostic imaging
  • Cerebrovascular Disorders / surgery
  • Contrast Media*
  • Forecasting
  • Humans
  • Microbubbles*
  • Neuroimaging / methods*
  • Ultrasonography / methods*
  • Ultrasonography, Interventional / methods

Substances

  • Contrast Media