Musculoskeletal Tumors

Amit Singla; David S Geller

doi:10.1016/j.pcl.2019.09.014

Musculoskeletal Tumors

Pediatr Clin North Am. 2020 Feb;67(1):227-245. doi: 10.1016/j.pcl.2019.09.014.

Authors

Amit Singla¹, David S Geller²

Affiliations

¹ Department of Orthopaedic Surgery, Montefiore Medical Center, 3400 Bainbridge Avenue, 6th Floor, Bronx, NY 10467, USA. Electronic address: dgeller@montefiore.org.
² Department of Orthopaedic Surgery, Montefiore Medical Center, 3400 Bainbridge Avenue, 6th Floor, Bronx, NY 10467, USA.

PMID: 31779834
DOI: 10.1016/j.pcl.2019.09.014

Abstract

Pediatric musculoskeletal tumors can arise in both bone and soft tissues. The overwhelming majority of these are benign; however, rarely, malignant neoplasms do occur. These are collectively termed sarcomas, indicating their mesenchymal origin. Sarcoma management requires careful adherence to the well-described tenets of tumor management. This article summarizes the basic principles and recent advances in the management of soft tissue and bone tumors.

Keywords: Biopsy; Bone tumors; Musculoskeletal tumors; Precision medicine; Sarcoma; Soft tissue tumors; Surgical margin; Translation research.

Publication types

Review

MeSH terms

Bone Neoplasms* / diagnosis
Bone Neoplasms* / therapy
Child
Humans
Sarcoma* / diagnosis
Sarcoma* / therapy
Soft Tissue Neoplasms* / diagnosis
Soft Tissue Neoplasms* / therapy