Maternal exposure to fine particulate matter during pregnancy induces progressive senescence of hematopoietic stem cells under preferential impairment of the bone marrow microenvironment and aids development of myeloproliferative disease

Leukemia. 2020 May;34(5):1481-1484. doi: 10.1038/s41375-019-0665-8. Epub 2019 Nov 27.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Factors
  • Animals
  • Bone Marrow / drug effects
  • Bone Marrow / pathology*
  • Cellular Senescence*
  • Female
  • Hematopoietic Stem Cells / drug effects
  • Hematopoietic Stem Cells / pathology*
  • Maternal Exposure / adverse effects*
  • Myeloproliferative Disorders / chemically induced
  • Myeloproliferative Disorders / pathology*
  • Particulate Matter / toxicity*
  • Pregnancy

Substances

  • Particulate Matter