GLP-2 Analogues as First Specific Treatment of Intestinal Failure

Abstract

Growth factors and other trophic hormones play an important role in the specific treatment of intestinal failure, with teduglutide being the first approved medication specifically for use in patients with intestinal failure in conjunction with specialized nutritional support. This article focusses on the mode of action, the pivotal study data, treatment response prediction as well as new substances in phase clinical trials.

Keywords: Growth factors; Intestinal failure; Mode of action; New substances in phase clinical trials; Pivotal study data; Specific treatment; Teduglutide; Treatment response prediction; Trophic hormones.