Measurement of Pulse Wave Signals and Blood Pressure by a Plastic Optical Fiber FBG Sensor

Sensors (Basel). 2019 Nov 21;19(23):5088. doi: 10.3390/s19235088.

Abstract

Fiber Bragg grating (FBG) sensors fabricated in silica optical fiber (Silica-FBG) have been used to measure the strain of human arteries as pulse wave signals. A variety of vital signs including blood pressure can be derived from these signals. However, silica optical fiber presents a safety risk because it is easily fractured. In this research, an FBG sensor fabricated in plastic optical fiber (POF-FBG) was employed to resolve this problem. Pulse wave signals were measured by POF-FBG and silica-FBG sensors for four subjects. After signal processing, a calibration curve was constructed by partial least squares regression, then blood pressure was calculated from the calibration curve. As a result, the POF-FBG sensor could measure the pulse wave signals with an signal to noise (SN) ratio at least eight times higher than the silica-FBG sensor. Further, the measured signals were substantially similar to those of an acceleration plethysmograph (APG). Blood pressure is measured with low error, but the POF-FBG APG correlation is distributed from 0.54 to 0.72, which is not as high as desired. Based on these results, pulse wave signals should be measured under a wide range of reference blood pressures to confirm the reliability of blood pressure measurement uses POF-FBG sensors.

Keywords: blood pressure; fiber Bragg grating; non-invasive measurement; partial least squares regression; plastic optical fiber; pulse wave signals.

MeSH terms

  • Algorithms
  • Blood Pressure / physiology*
  • Blood Pressure Determination / instrumentation*
  • Calibration
  • Heart Rate / physiology*
  • Humans
  • Least-Squares Analysis
  • Optical Fibers
  • Physical Phenomena
  • Plastics / chemistry*
  • Reproducibility of Results
  • Signal Processing, Computer-Assisted / instrumentation

Substances

  • Plastics