Management of status epilepticus in adults. Position paper of the Italian League against Epilepsy

Fabio Minicucci; Monica Ferlisi; Francesco Brigo; Oriano Mecarelli; Stefano Meletti; Umberto Aguglia; Roberto Michelucci; Massimo Mastrangelo; Nicola Specchio; Stefano Sartori; Paolo Tinuper

doi:10.1016/j.yebeh.2019.106675

Management of status epilepticus in adults. Position paper of the Italian League against Epilepsy

Epilepsy Behav. 2020 Jan:102:106675. doi: 10.1016/j.yebeh.2019.106675. Epub 2019 Nov 22.

Authors

Affiliations

¹ Epilepsy Center, Unit of Neurophysiology, Neurological Department, IRCCS San Raffaele Hospital, Milan, Italy. Electronic address: minicucci.fabio@hsr.it.
² Division of Neurology A, Azienda Ospedaliera Universitaria Integrata, Verona, Italy. Electronic address: monica.ferlisi@aovr.veneto.it.
³ Division of Neurology, "Franz Tappeiner" Hospital, Merano, Italy; Department of Neuroscience, Biomedicine and Movement Science, University of Verona, Verona, Italy.
⁴ Department of Human Neuroscience, Sapienza University of Rome, Rome, Italy. Electronic address: oriano.mecarelli@uniroma1.it.
⁵ Department of Biomedical, Metabolic and Neural Sciences, Center for Neurosciences and Neurotechnology, University of Modena and Reggio Emilia, Modena, Italy; Neurology Unit, OCB Hospital, Azienda Ospedaliero-Universitaria di Modena, Modena, Italy. Electronic address: stefano.meletti@unimore.it.
⁶ Epilepsy Center, Department of Medical and Surgical Sciences Regional, Magna Graecia University of Catanzaro, Catanzaro, Italy.
⁷ IRCCS Istituto delle Scienze Neurologiche di Bologna, Unit of Neurology, Bellaria Hospital, Bologna, Italy. Electronic address: roberto.michelucci@isnb.it.
⁸ Pediatric Neurology Unit, "V. Buzzi" Children's Hospital, Pediatrics Department, ASST Fatebenefratelli Sacco, Milan, Italy. Electronic address: massimo.mastrangelo@asst-fbf-sacco.it.
⁹ Department of Neuroscience, IRCCS Bambino Gesù Children's Hospital, Rome, Italy. Electronic address: nicola.specchio@opbg.net.
¹⁰ Paediatric Neurology and Neurophysiology Unit, Department of Women's and Children's Health, University Hospital of Padua, Padua, Italy. Electronic address: stefano.sartori@unipd.it.
¹¹ IRCCS Istituto delle Scienze Neurologiche, Bellaria Hospital, Bologna, Italy; Department of Biomedical and Neuromotor Sciences, University of Bologna, Italy. Electronic address: paolo.tinuper@unibo.it.

PMID: 31766004
DOI: 10.1016/j.yebeh.2019.106675

Abstract

Since the publication of the Italian League Against Epilepsy guidelines for the treatment of status epilepticus in 2006, advances in the field have ushered in improvements in the therapeutic arsenal. The present position paper provides neurologists, epileptologists, neurointensive care specialists, and emergency physicians with updated recommendations for the treatment of adult patients with status epilepticus. The aim is to standardize treatment recommendations in the care of this patient population.

Keywords: Antiepileptic drugs; Epilepsy; Italian League against Epilepsy; Position paper; Status epilepticus; Treatment.

Publication types

Review

MeSH terms

Adult
Anticonvulsants / therapeutic use
Disease Management*
Epilepsy / epidemiology
Epilepsy / therapy*
Humans
Italy / epidemiology
Neurosurgical Procedures / methods
Neurosurgical Procedures / standards
Randomized Controlled Trials as Topic / methods
Randomized Controlled Trials as Topic / standards*
Status Epilepticus / epidemiology
Status Epilepticus / therapy*

Substances

Anticonvulsants