Amabiloid A from Crinum × amabile Donn ex Ker Gawl

Kanda Panthong; Kornkanok Ingkaninan

doi:10.1080/14786419.2019.1693561

Amabiloid A from Crinum × amabile Donn ex Ker Gawl

Nat Prod Res. 2021 Oct;35(19):3220-3225. doi: 10.1080/14786419.2019.1693561. Epub 2019 Nov 25.

Authors

Kanda Panthong^{1

2}, Kornkanok Ingkaninan³

Affiliations

¹ Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Prince of Songkla University, Songkhla, Thailand.
² Natural Products Research Center of Excellence, Faculty of Science, Prince of Songkla University, Songkhla, Thailand.
³ Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok, Thailand.

PMID: 31762341
DOI: 10.1080/14786419.2019.1693561

Abstract

A new alkaloid, amabiloid A (1) was isolated from Crinum amabile along with eleven known compounds. Their structures were determined by 1D and 2D NMR spectroscopic data. In addition, the acetyl- and butyrylcholinesterase inhibitory activities of the isolated compounds were evaluated.

Keywords: Amaryllidaceae; Crinum amabile; acetylcholinesterase; amabiloid; butyrylcholinesterase.

MeSH terms

Amaryllidaceae Alkaloids* / isolation & purification
Amaryllidaceae Alkaloids* / pharmacology
Butyrylcholinesterase
Cholinesterase Inhibitors / isolation & purification
Cholinesterase Inhibitors / pharmacology*
Crinum* / chemistry
Phytochemicals / isolation & purification
Phytochemicals / pharmacology
Plant Extracts

Substances

Amaryllidaceae Alkaloids
Cholinesterase Inhibitors
Phytochemicals
Plant Extracts
Butyrylcholinesterase