R-Loops as Promoters of Antisense Transcription

Ana G Rondón; Andrés Aguilera

doi:10.1016/j.molcel.2019.11.001

R-Loops as Promoters of Antisense Transcription

Mol Cell. 2019 Nov 21;76(4):529-530. doi: 10.1016/j.molcel.2019.11.001.

Authors

Ana G Rondón¹, Andrés Aguilera²

Affiliations

¹ Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER), Universidad de Sevilla- CSIC, Seville, Spain.
² Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER), Universidad de Sevilla- CSIC, Seville, Spain. Electronic address: aguilo@us.es.

PMID: 31756322
DOI: 10.1016/j.molcel.2019.11.001

Abstract

The study by Tan-Wong et al. (2019) in this issue of Molecular Cell reveals a capacity of R-loops to promote antisense transcription expanding our view of the features that a DNA region may have to act as a promoter.

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MeSH terms

Animals
Mammals*
Promoter Regions, Genetic
R-Loop Structures*