Nocardia Keratitis

Excerpt

Nocardia is a Gram-variable, aerobic, weakly acid-fast bacteria that rarely causes ocular disease, of which corneal infection is the most common. The diagnosis of Nocardia keratitis is often missed or delayed due to a lack of familiarity or a non-specific presentation, which may mimic other more common causative organisms. Notably, Nocardia keratitis has a variable response to most first-line medications used for bacterial keratitis, such as fluoroquinolones. Thus, patients may suffer from significant morbidity until reaching a proper diagnosis.