The Evolving Role of Radiotherapy for Head and Neck Cancer

Hematol Oncol Clin North Am. 2020 Feb;34(1):91-108. doi: 10.1016/j.hoc.2019.08.019. Epub 2019 Oct 15.

Abstract

The length and quality of head and neck cancer survivorship continues to meaningfully improve. Radiotherapy has been central to this process through advances in treatment delivery, fractionation schemas, radiosensitizing systemic therapy, and thoughtful interplay with technical surgical improvements. The future looks brighter still, with ongoing progress in targeted biologic therapy, immuno-oncology, and molecular-genetic tumor characterization for personalized treatment. Head and neck cancer, a disease once fraught with nihilism and failure, is evolving into a major success story of modern multidisciplinary cancer care.

Keywords: Advances; Head and neck cancer; Radiotherapy; Review.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Dose Fractionation, Radiation*
  • Head and Neck Neoplasms / radiotherapy*
  • Humans
  • Radiation-Sensitizing Agents / therapeutic use*

Substances

  • Radiation-Sensitizing Agents