Lactate dehydrogenase isoenzyme-1 in the mediastinal yolk sac tumor

M Ito; T Taki; A Mitsuoka; M Miyake

doi:10.1007/BF02471467

Lactate dehydrogenase isoenzyme-1 in the mediastinal yolk sac tumor

Jpn J Surg. 1988 Jul;18(4):419-22. doi: 10.1007/BF02471467.

Authors

M Ito¹, T Taki, A Mitsuoka, M Miyake

Affiliation

¹ Department of Thoracic Surgery, Kyoto University, Japan.

PMID: 3172584
DOI: 10.1007/BF02471467

Abstract

LDH isozymes in both the serum and tumor tissues of 4 patients with mediastinal yolk sac tumors, and in the cystic content of tumors transplanted into nude mice was examined. Our findings suggested that LDH-1, along with AFP, is an important marker of this tumor, and that LDH isozyme study is necessary for its diagnosis.

MeSH terms

Adolescent
Adult
Animals
Biomarkers, Tumor / analysis*
Humans
Isoenzymes
L-Lactate Dehydrogenase / analysis*
L-Lactate Dehydrogenase / biosynthesis
Male
Mediastinal Neoplasms / diagnosis*
Mediastinal Neoplasms / enzymology
Mediastinal Neoplasms / surgery
Mesonephroma / diagnosis*
Mesonephroma / enzymology
Mesonephroma / surgery
Mice
Mice, Nude
Neoplasm Transplantation

Substances

Biomarkers, Tumor
Isoenzymes
L-Lactate Dehydrogenase