Recent advances in the induction of labor

F1000Res. 2019 Oct 30:8:F1000 Faculty Rev-1829. doi: 10.12688/f1000research.17587.1. eCollection 2019.

Abstract

The rate of labor induction is steadily increasing and, in industrialized countries, approximately one out of four pregnant women has their labor induced. Induction of labor should be considered when the benefits of prompt vaginal delivery outweigh the maternal and/or fetal risks of waiting for the spontaneous onset of labor. However, this procedure is not free of risks, which include an increase in operative vaginal or caesarean delivery and excessive uterine activity with risk of fetal heart rate abnormalities. A search for "Induction of Labor" retrieves more than 18,000 citations from 1844 to the present day. The aim of this review is to summarize the controversies concerning the indications, the methods, and the tools for evaluating the success of the procedure, with an emphasis on the scientific evidence behind each.

Keywords: Induction of labor; prediction of successful induction; prostaglandins.

Publication types

  • Review

MeSH terms

  • Cesarean Section
  • Female
  • Humans
  • Labor, Induced*
  • Oxytocics*
  • Pregnancy

Substances

  • Oxytocics

Grants and funding

The author(s) declared that no grants were involved in supporting this work.