Bioavailability of nanoemulsion formulations vs conventional fat soluble preparations of cholecalciferol (D3) - An overview

J Clin Orthop Trauma. 2019 Nov-Dec;10(6):1094-1096. doi: 10.1016/j.jcot.2019.07.014. Epub 2019 Jul 31.

Abstract

Vitamin D deficiency is recognized as a pandemic affecting all ages and strata of population. The endogenous cutaneous synthesis of vitamin D is insufficient to maintain normal body requirement which necessitates the need for vitamin D supplementation or food-fortification. Conventional fat-soluble preparations of vitamin D have been traditionally used for prevention and therapeutic purposes. Recent advances in technology have enabled delivery of vitamin D through nanoemulsion formulations which ensure higher absorption and drug delivery. The following review briefly discusses the issues of bioavailability of nanoemulsion preparation of vitamin D vis-a-vis conventional fat soluble preparations.

Keywords: Fat-soluble; Nanoemulsion; Nanotechnology; Preparations; Vitamin D.

Publication types

  • Review