Functional modulation of cytochrome C upon specific binding to DNA nanoribbons

Xiangyuan Ouyang; Si-Yao Wang; Ting Liu; Yong-An Ren; Mei-Fang Wang; Fang-Fang Chen; Li-Li Wang

doi:10.1039/c9cc05427h

Functional modulation of cytochrome C upon specific binding to DNA nanoribbons

Chem Commun (Camb). 2019 Dec 4;55(93):14074-14077. doi: 10.1039/c9cc05427h. Epub 2019 Nov 7.

Authors

Xiangyuan Ouyang¹, Si-Yao Wang¹, Ting Liu¹, Yong-An Ren¹, Mei-Fang Wang¹, Fang-Fang Chen¹, Li-Li Wang¹

Affiliation

¹ Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Key Laboratory of Modern Separation Science in Shaanxi Province, College of Chemistry & Materials Science, Northwest University, Xi'an, Shaanxi 710127, P. R. China. llwang@nwu.edu.cn ouyangxy@nwu.edu.cn.

PMID: 31696869
DOI: 10.1039/c9cc05427h

Abstract

We discovered that the function of cytochrome C can be modulated by DNA nanoribbons. Meanwhile, the interplay between the DNA nanoribbons and the native cytochrome C and the possible mechanisms are also discussed.

MeSH terms

Animals
Catalysis
Cytochromes c / chemistry
Cytochromes c / metabolism*
DNA / chemistry
DNA / metabolism*
Guaiacol / chemistry
Horses
Nanostructures / chemistry*
Oxidation-Reduction
Peroxidases / chemistry
Peroxidases / metabolism*
Protein Binding

Substances

Guaiacol
Cytochromes c
DNA
Peroxidases