[Associated factors to the inadequate response to hepatitis B vaccine in HIV patients]

Rev Gastroenterol Peru. 2019 Jul-Sep;39(3):252-257.
[Article in Spanish]

Abstract

Objective: To establish the relationship among age, sex, body mass index, consumption of alcoholic beverages and cigarettes with the inadequate response to the vaccine against Hepatitis B in patients with HIV infection who were treated in the Clinical Unit of Infectious and Tropical Diseases of the Regional Hospital of Trujillo - Peru, from 2014 to 2015.

Materials and methods: The study was observational, retrospective, cross-sectional, type cases and controls.

Results: In the vaccinated patients, it was found that the age ≥ 50 years old; with OR = 3.4 and CD4 < 200, with OR = 35.0, are the risk factors to get the inadequate response to the vaccine against Hepatitis B.

Conclusions: There is a relationship between the re-count of cells CD4 < 00 and the age over 50 years old with an Inadequate response to the vaccination against hepatitis B in HIV-infected patients in the Regional Hospital of Trujillo.

Publication types

  • Observational Study

MeSH terms

  • Age Factors
  • Alcohol Drinking / adverse effects
  • Body Mass Index
  • Cigarette Smoking / adverse effects
  • Cross-Sectional Studies
  • Female
  • HIV Infections / immunology*
  • Hepatitis B Vaccines / immunology*
  • Humans
  • Immunogenicity, Vaccine*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Sex Factors

Substances

  • Hepatitis B Vaccines