Apixaban-induced fatal liver injury with a cholestatic pattern: A case report and brief review of the Literature

Eur J Intern Med. 2019 Dec:70:e17-e18. doi: 10.1016/j.ejim.2019.10.003. Epub 2019 Nov 2.

Authors

Federico Pasin¹, Maria Del Pilar Esteban², Sophie Testa²

Affiliations

¹ Internal Medicine Unit, ASST Cremona, Cremona, Italy. Electronic address: f.pasin@ospedale.cremona.it.
² Haemostasis and Thrombosis Center, ASST Cremona, Cremona, Italy.

PMID: 31685349
DOI: 10.1016/j.ejim.2019.10.003

No abstract available

Keywords: Apixaban; Direct oral anticoagulant; Drug-induced liver injury; Hepatotoxicity; Jaundice.

Publication types

Case Reports
Review

MeSH terms

Aged, 80 and over
Atrial Fibrillation / drug therapy
Chemical and Drug Induced Liver Injury / etiology*
Cholestasis
Factor Xa Inhibitors / adverse effects*
Fatal Outcome
Female
Humans
Pyrazoles / adverse effects*
Pyridones / adverse effects*

Substances

Factor Xa Inhibitors
Pyrazoles
Pyridones
apixaban