Medical Management of Inflammatory Bowel Disease

Surg Clin North Am. 2019 Dec;99(6):1223-1235. doi: 10.1016/j.suc.2019.08.011. Epub 2019 Sep 21.

Abstract

Inflammatory bowel disease has become a growing concern worldwide. The chronic and progressive nature of inflammatory bowel disease poses significant challenges to the treatment and management of affected patients, straining health care resources. Therapeutic options and optimal management strategies have evolved dramatically. The treat-to-target strategy has shifted focus toward identifiable and attainable treatment targets and with the ability to optimize tight control. Advancements in our understanding of the pathophysiology led to therapeutic mechanisms that have a more narrowed focus toward gut-specific targets, improving safety profiles.

Keywords: Inflammatory bowel disease; Management; Therapeutic drug monitoring; Treat-to-target strategy; Treatment.

Publication types

  • Review

MeSH terms

  • Biological Products / administration & dosage*
  • Biological Products / pharmacology
  • Conservative Treatment / methods*
  • Disease Management
  • Female
  • Follow-Up Studies
  • Humans
  • Immunosuppressive Agents / administration & dosage*
  • Inflammatory Bowel Diseases / diagnosis
  • Inflammatory Bowel Diseases / therapy*
  • Male
  • Patient Selection
  • Recurrence
  • Retreatment
  • Risk Assessment
  • Time Factors
  • Treatment Outcome

Substances

  • Biological Products
  • Immunosuppressive Agents