Achievement of cardiovascular risk factor targets according to sex and previous history of cardiovascular disease in type 2 diabetes: A population-based study

J Diabetes Complications. 2019 Dec;33(12):107445. doi: 10.1016/j.jdiacomp.2019.107445. Epub 2019 Sep 12.

Abstract

Aims: The main objective was to assess, using real-practice primary care records, the degree of control of cardiovascular risk factor targets. Records were stratified by the presence of previous history or cardiovascular disease (CVD), and sex differences in the fulfillment profile were analyzed.

Methods: This is a cross-sectional population-based study conducted in Spain. Type 2 diabetes patients over 20 years old (n = 32,638) were identified from primary care electronic health records, and the following information was extracted: glycated hemoglobin (HbA1c), systolic and diastolic blood pressure (SBP and DBP), LDL and HDL cholesterol levels, triglycerides, BMI and smoking history.

Results: Patients with CVD had worse control of HbA1c than patients without it, (HbA1c < 7% 56.9% vs. 61.2%) but better control of BP (<130/80: 43.5% vs 38.2%) and lipids. In the group without prior CVD history, women had worse control of HbA1c, LDL, HDL, BMI and triglycerides and better control of blood pressure and smoking. These differences were maintained or accentuated in the group with previous CVD.

Conclusions: Women had poorer control of CV risk factors in both groups, and the sex-gap is accentuated in patients with previous CVD.

Keywords: Cardiovascular risk factors; Control targets; Primary care; Type 2 diabetes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cardiovascular Diseases / epidemiology
  • Cardiovascular Diseases / etiology
  • Cardiovascular Diseases / metabolism
  • Cardiovascular Diseases / therapy*
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 2 / complications
  • Diabetes Mellitus, Type 2 / epidemiology
  • Diabetes Mellitus, Type 2 / metabolism
  • Diabetes Mellitus, Type 2 / therapy*
  • Female
  • Glycated Hemoglobin / metabolism
  • Glycemic Control / statistics & numerical data
  • Heart Disease Risk Factors*
  • Humans
  • Male
  • Middle Aged
  • Patient Care Planning* / statistics & numerical data
  • Primary Health Care / methods
  • Primary Health Care / statistics & numerical data
  • Risk Factors
  • Sex Factors
  • Spain / epidemiology
  • Young Adult

Substances

  • Glycated Hemoglobin A