Hepcidin and iron: novel findings for elite female rugby Sevens players

J Sports Med Phys Fitness. 2020 Feb;60(2):289-293. doi: 10.23736/S0022-4707.19.10096-5. Epub 2019 Oct 25.

Abstract

Background: Iron deficiency is a common deficiency disease worldwide with athletes at increased risk.

Methods: A proposed new mechanism of exercise-induced iron deficiency in athletes involves the iron-regulatory hormone hepcidin, however, there is limited information on this amongst elite athletes. This study describes iron status in elite female rugby Sevens players.

Results: Blood samples were collected at the start and mid-season and analyzed for serum iron, serum ferritin (SF), soluble transferring receptor (sTfR), high sensitivity C-reactive Protein (hsCRP) and hepcidin. Of the 17 players 18% were iron deficient (SF<30 µg/L) with 29-35% of players with sub-optimal iron stores at some point during the study (SF<45 µg/L). Serum hepcidin was strongly correlated with SF (r=0.61, P=0.0001).

Conclusions: Some elite female rugby Sevens players have sub-optimal iron stores over the course of a season.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Athletes / statistics & numerical data
  • C-Reactive Protein / analysis
  • Female
  • Ferritins / blood
  • Football / statistics & numerical data
  • Hepcidins / blood*
  • Humans
  • Iron / blood*
  • Iron Deficiencies
  • Longitudinal Studies
  • Young Adult

Substances

  • HAMP protein, human
  • Hepcidins
  • C-Reactive Protein
  • Ferritins
  • Iron