Risky Alcohol Consumption and Associated Health Behaviour Among HIV-Positive and HIV-Negative Patients in a UK Sexual Health and HIV Clinic: A Cross-Sectional Questionnaire Study

AIDS Behav. 2020 Jun;24(6):1717-1726. doi: 10.1007/s10461-019-02714-2.

Abstract

Alcohol misuse has been associated with negative consequences among HIV-positive patients. Data on real prevalence of risky alcohol consumption among the HIV-positive population in the UK are lacking. A cross-sectional questionnaire study using standardised validated instruments among HIV-positive (n = 227) and HIV-negative (n = 69) patients was performed. The prevalence of risky alcohol consumption (AUDIT) and associations with depressive symptoms (PHQ-9), problematic drug use (DUDIT), adherence to ART (CASE Adherence Index), sexual behaviour and demographic characteristics were assessed among both patient groups independently. A quarter (25.1%) of HIV-positive patients and 36.1% of HIV-negative patients reported risky alcohol consumption (AUDIT-score ≥ 8). In the multivariable analysis among HIV-positive patients depressive symptoms (p = 0.03) and problematic drug use (p = 0.007) were associated with risky alcohol consumption. Among HIV-negative patients these associations were not present. Risky alcohol consumption among HIV-positive patients is prevalent, and together with depressive symptoms and problematic drug use, may influence HIV-disease progression and patients' wellbeing.

El abuso del alcohol se ha asociado con consecuencias negativas a la salud de pacientes VIH-positivos. La prevalencia actual del consumo riesgoso de alcohol en la población VIH-positiva en el Reino Unido es desconocida. Este estudio transversal, basado en un cuestionario y usando instrumentos validados y estandarizados, incluyó pacientes VIH-positivos (n = 227) y VIH-negativos (n = 69). La prevalencia del consumo riesgoso de alcohol (AUDIT) y su asociación con síntomas de depresión (PHQ-9), uso problemático de drogas (DUDIT), adherencia a la TAR (CASE Adhernce Index), comportamiento sexual características demográficas que fueron evaluadas independientemente en cada grupo de pacientes. La cuarta parte (25.1%) de los pacientes VIH-positivos y 36.1% de los VIH-negativos reportaron consumo riesgoso de alcohol (AUDIT score ≥ 8). En pacientes VIH-positivos, en el análisis multivariable síntomas depresivos (p = 0.03) y uso problemático de drogas (p = 0.007) estuvieron asociados con consumo riesgoso de alcohol. En pacientes VIH-negativos no se observaron tales asociaciones. En pacientes VIH-positivos el consumo riesgoso de alcohol es prevalente y conjuntamente con la presencia de síntomas depresivos y el uso problemático de drogas, puede influenciar la progresión de la enfermedad por VIH y el bienestar de los pacientes.

Keywords: AUDIT; Alcohol misuse; Drug use; HIV; Mood disorders.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Alcohol Drinking / epidemiology*
  • Alcohol Drinking / psychology
  • Alcohol-Related Disorders / diagnosis*
  • Alcohol-Related Disorders / epidemiology*
  • Alcohol-Related Disorders / psychology
  • Antiretroviral Therapy, Highly Active
  • Cross-Sectional Studies
  • Depression / epidemiology
  • Depression / psychology
  • Female
  • HIV Infections / drug therapy
  • HIV Infections / epidemiology*
  • HIV Infections / psychology
  • HIV Seropositivity
  • Health Behavior*
  • Humans
  • Male
  • Medication Adherence / psychology*
  • Medication Adherence / statistics & numerical data
  • Middle Aged
  • Prevalence
  • Sexual Behavior / psychology*
  • Sexual Behavior / statistics & numerical data
  • Sexual Health
  • Socioeconomic Factors
  • Substance-Related Disorders / epidemiology
  • Substance-Related Disorders / psychology
  • Surveys and Questionnaires
  • United Kingdom / epidemiology
  • Unsafe Sex