State-of-the-Art and Prospects of Biomolecules: Incorporation in Functional Metal-Organic Frameworks

Top Curr Chem (Cham). 2019 Oct 30;377(6):34. doi: 10.1007/s41061-019-0258-z.

Abstract

Given the unique properties of metal-organic frameworks (MOFs) including adjustable porosity, high surface area, and easy modification, they have attracted great attention as excellent solid supports for the incorporation of biomolecules. The formed biomolecules-MOFs composites show promising prospects in various fields such as biocatalysis, drug delivery, and biosensing. This review focuses on the state-of-the-art of biomolecules-incorporation using MOFs. Moreover, the relationship between properties of MOFs and biomolecules-incorporation is also discussed and highlighted. We hope this work will inspire the innovation in this emerging field for highly efficient synthesis of biomolecules-MOFs composites with various properties and advanced applications.

Keywords: Application; Biomolecules; Incorporation; Metal–organic frameworks.

Publication types

  • Review

MeSH terms

  • Adsorption
  • DNA / chemistry
  • Metal-Organic Frameworks / chemistry*
  • Porosity
  • Proteins / chemistry
  • Surface Properties

Substances

  • Metal-Organic Frameworks
  • Proteins
  • DNA