JAK inhibitors alter NK cell functions and may impair immunosurveillance against lymphomagenesis

Cell Mol Immunol. 2020 May;17(5):552-553. doi: 10.1038/s41423-019-0320-3. Epub 2019 Oct 29.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carcinogenesis / drug effects
  • Carcinogenesis / pathology*
  • Humans
  • Janus Kinase Inhibitors / pharmacology
  • Janus Kinase Inhibitors / therapeutic use*
  • Killer Cells, Natural / drug effects
  • Killer Cells, Natural / immunology*
  • Lymphoma / drug therapy*
  • Lymphoma / immunology*
  • Monitoring, Immunologic*
  • Piperidines / pharmacology
  • Piperidines / therapeutic use
  • Pyrimidines / pharmacology
  • Pyrimidines / therapeutic use

Substances

  • Janus Kinase Inhibitors
  • Piperidines
  • Pyrimidines
  • tofacitinib