Renovascular Hypertension

Endocrinol Metab Clin North Am. 2019 Dec;48(4):765-778. doi: 10.1016/j.ecl.2019.08.007. Epub 2019 Sep 19.

Abstract

Renovascular disease (RVD) is a major cause of secondary hypertension. Atherosclerotic renal artery stenosis is the most common type of RVD followed by fibromuscular dysplasia. It has long been recognized as the prototype of angiotensin-dependent hypertension. However, the mechanisms underlying the physiopathology of hypertensive occlusive vascular renal disease are complex and distinction between the different causes of RVD should be made. Recognition of these distinct types of RVD with different degrees of renal occlusive disease is important for management. The greatest challenge is to individualize and implement the best approach for each patient in the setting of widely different comorbidities.

Keywords: Hypertension; Ischemic nephropathy; Renal artery stenosis; Renin and angiotensin; Renovascular disease.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Fibromuscular Dysplasia* / complications
  • Fibromuscular Dysplasia* / diagnosis
  • Fibromuscular Dysplasia* / physiopathology
  • Fibromuscular Dysplasia* / therapy
  • Humans
  • Hypertension, Renal* / diagnosis
  • Hypertension, Renal* / etiology
  • Hypertension, Renal* / physiopathology
  • Hypertension, Renal* / therapy
  • Hypertension, Renovascular* / diagnosis
  • Hypertension, Renovascular* / etiology
  • Hypertension, Renovascular* / physiopathology
  • Hypertension, Renovascular* / therapy
  • Nephritis* / diagnosis
  • Nephritis* / etiology
  • Nephritis* / physiopathology
  • Nephritis* / therapy
  • Renal Artery Obstruction* / complications
  • Renal Artery Obstruction* / diagnosis
  • Renal Artery Obstruction* / physiopathology
  • Renal Artery Obstruction* / therapy

Supplementary concepts

  • Hypertensive Nephropathy