Knee septic arthritis caused by α-hemolytic Streptococcus in a patient with a recent history of knee arthroscopy: a case report

BMC Infect Dis. 2019 Oct 24;19(1):887. doi: 10.1186/s12879-019-4556-4.

Abstract

Background: Arthroscopic partial meniscectomy is a common procedure in orthopedic practice. Infections are uncommon complications of this procedure with an incidence rate of 0,01% - 3,4%. Staphylococcus spp are the predominant causative agents in such cases. We present a case of knee septic arthritis caused by α-hemolytic Streptococcus.

Case presentation: A 22-year-old woman diagnosed with obesity (body mass index [BMI] 35 kg/m2) but with no other major comorbidities underwent an arthroscopic selective meniscectomy with administration of intravenous cefazolin for antibiotic prophylaxis. After an uneventful period of 2 months, the patient returned with pain, fever and a discharging sinus at the site of anterolateral arthroscopic portal. Blood tests and magnetic resonance imaging revealed osteomyelitis involving the tibial plate. Cultures of synovial fluid obtained from the knee and a pharyngeal swab yielded α-hemolytic Streptococcus. Five days later, the patient underwent arthroscopic debridement with partial synovectomy. Intraoperative specimens yielded α-hemolytic Streptococcus. The patient received intravenous piperacillin/tazobactam, followed by an associative regimen of amoxicillin and clindamycin with clinical, laboratory and instrumental evidence of symptom resolution.

Conclusion: The incidence of knee septic arthritis after arthroscopic partial meniscectomy is 0.01-3.4%. This infection is usually caused by Staphylococcus spp. and in rare cases by commensal bacteria, such as α-hemolytic streptococci, secondary to transient bacteremia. Screening of the colonized area is important to prevent possible transient bacteremia. Diagnosis is based on isolation of the causative organisms from synovial fluid cultures, and treatment comprises arthroscopic debridement with individualized systemic antibiotic therapy based on the results of an antibiogram.

Keywords: Arthroscopic partial meniscectomy; Knee; Septic arthritis; Streptococcus spp.

Publication types

  • Case Reports

MeSH terms

  • Administration, Intravenous
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use
  • Arthritis, Infectious / drug therapy
  • Arthritis, Infectious / etiology
  • Arthritis, Infectious / microbiology*
  • Arthroscopy / adverse effects*
  • Bacteremia / drug therapy*
  • Bacteremia / etiology
  • Debridement / methods
  • Female
  • Humans
  • Meniscectomy / adverse effects*
  • Osteoarthritis, Knee / drug therapy
  • Osteoarthritis, Knee / microbiology*
  • Streptococcal Infections / drug therapy*
  • Streptococcal Infections / etiology
  • Streptococcal Infections / microbiology
  • Streptococcus / isolation & purification
  • Streptococcus / pathogenicity
  • Synovial Fluid / microbiology
  • Young Adult

Substances

  • Anti-Bacterial Agents