Highly stereoselective intramolecular Buchner reaction of diazoacetamides catalyzed by a Ru(ii)-Pheox complex

Chem Commun (Camb). 2019 Nov 18;55(89):13398-13401. doi: 10.1039/c9cc06889a. Epub 2019 Oct 22.

Abstract

This work reports the first efficient enantioselective intramolecular Buchner reaction of diazoacetamides. The Ru(ii)-Pheox catalyst was shown to be highly efficient in this transformation in terms of both the regio- and enantioselectivity (up to 99% ee) giving the desired products in quantitative yield.