Role of biological agents in treatment of rheumatoid arthritis

Shing T Law; Peter C Taylor

doi:10.1016/j.phrs.2019.104497

Role of biological agents in treatment of rheumatoid arthritis

Pharmacol Res. 2019 Dec:150:104497. doi: 10.1016/j.phrs.2019.104497. Epub 2019 Oct 17.

Authors

Shing T Law¹, Peter C Taylor²

Affiliations

¹ Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, OX3 7LD, UK.
² Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, OX3 7LD, UK. Electronic address: peter.taylor@kennedy.ox.ac.uk.

PMID: 31629903
DOI: 10.1016/j.phrs.2019.104497

Abstract

Advances in understanding of the pathophysiology of rheumatoid arthritis with concurrent advances in protein engineering led to the development of biological disease-modifying antirheumatic drugs which have dramatically revolutionized the treatment of this condition. This review article focuses on the role of biological agents currently employed in the treatment of rheumatoid arthritis, as well as novel biological agents in development.

Keywords: Biological disease-modifying antirheumatic drugs; Review; Rheumatoid arthritis.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Antirheumatic Agents / therapeutic use*
Arthritis, Rheumatoid / drug therapy*
Biological Factors / therapeutic use*
Humans

Substances

Antirheumatic Agents
Biological Factors

Grants and funding

DH_/Department of Health/United Kingdom