Neuroprotective and Anti-Obesity Effects of Tocotrienols

J Nutr Sci Vitaminol (Tokyo). 2019;65(Supplement):S185-S187. doi: 10.3177/jnsv.65.S185.

Abstract

Vitamin E is a natural lipophilic vitamin, and the most famous function of vitamin E is an antioxidant activity. Because we have α-tocopherol transfer protein, many vitamin E-related reports are about α-tocopherol. Recently, other vitamin E isoforms, tocotrienols are focusing. Because tocotrienols have unique biological functions such as induction of apoptosis, neuroprotective and anti-obesity effects. Tocotrienols contain in annatto, palm, whole wheat and rice bran. Rice is a typical food in the East Asian countries and Japan. Recently, intake of whole rice is a popular in young women of Japan. Previously, we demonstrated that treatment with tocotrienols on the neuronal cells shows a strong antioxidant effect compared to the tocopherols. In this review, I introduce about neuroprotective and anti-obesity effects of tocotrienols. I would like to show daily intake of whole rice is very good for our health in this review.

Keywords: anti-obesity; bran; neuron; oxidative stress; tocotrienols.

Publication types

  • Review

MeSH terms

  • Adult
  • Anti-Obesity Agents / pharmacology*
  • Diet, Healthy / methods
  • Eating
  • Female
  • Humans
  • Male
  • Neuroprotective Agents / pharmacology*
  • Obesity / diet therapy
  • Oryza / chemistry*
  • Tocotrienols / pharmacology*
  • Vitamins / pharmacology*

Substances

  • Anti-Obesity Agents
  • Neuroprotective Agents
  • Tocotrienols
  • Vitamins