Embracing the complexity: Older adults with cancer-related cognitive decline-A Young International Society of Geriatric Oncology position paper

Mackenzi Pergolotti; Nicolò Matteo Luca Battisti; Lynne Padgett; Alix G Sleight; Maya Abdallah; Robin Newman; Kathleen Van Dyk; Kelley R Covington; Grant R Williams; Frederiek van den Bos; YaoYao Pollock; Elizabeth A Salerno; Allison Magnuson; Isabella F Gattás-Vernaglia; Tim A Ahles

doi:10.1016/j.jgo.2019.09.002

Embracing the complexity: Older adults with cancer-related cognitive decline-A Young International Society of Geriatric Oncology position paper

J Geriatr Oncol. 2020 Mar;11(2):237-243. doi: 10.1016/j.jgo.2019.09.002. Epub 2019 Oct 14.

Authors

Affiliations

¹ ReVital Cancer Rehabilitation, Select Medical, 4174 Gettysburg Rd, Mechanicsburg, PA 17055, USA; Department of Occupational Therapy - College of Health and Human Sciences, Colorado State University, 200 Occupational Therapy Building, Fort Collins, CO 80523-1573, USA. Electronic address: mpergolotti@selectmedical.com.
² Department of Medicine - Breast Unit, The Royal Marsden NHS Foundation Trust, Downs Road, Sutton Surrey SM2 5PT, United Kingdom. Electronic address: nicolo.battisti@rmh.nhs.uk.
³ Veterans Affairs Medical Center, Washington, DC, USA.
⁴ Outcomes Research Branch, Healthcare Delivery Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, USA. Electronic address: alix.sleight@nih.gov.
⁵ Department of Internal Medicine, University of Massachusetts Medical School - Baystate Medical Center, 759 Chestnut St., Springfield, MA, 01199, USA. Electronic address: maya.abdallahmd@baystatehealth.org.
⁶ Department of Occupational Therapy, Boston University Sargent College of Health and Rehabilitation Sciences, 635 Commonwealth Avenue, Boston, MA 02215, USA. Electronic address: newmanro@bu.edu.
⁷ Jonsson Comprehensive Cancer Center, Cancer Prevention and Control Research, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: KVanDyk@mednet.ucla.edu.
⁸ ReVital Cancer Rehabilitation, Select Medical, 4174 Gettysburg Rd, Mechanicsburg, PA 17055, USA; Department of Occupational Therapy - College of Health and Human Sciences, Colorado State University, 200 Occupational Therapy Building, Fort Collins, CO 80523-1573, USA. Electronic address: Kelley.Covington@colostate.edu.
⁹ Divisions of Hematology/Oncology & Gerontology, Geriatrics, and Palliative Care, Institute for Cancer Outcomes and Survivorship, The University of Alabama at Birmingham, 1670 University Blvd, Birmingham, AL 35233, USA. Electronic address: grwilliams@uabmc.edu.
¹⁰ Departement of Geriatric Medicine, University Medical Centre Utrecht, Heidelberglaan 100, 3584, CX, Utrecht, Netherlands. Electronic address: f.vandenbos@umcutrecht.nl.
¹¹ Geriatric Oncology Fellowship Program, University of California, San Francisco, 1600 Divisadero St, San Francisco, CA 94115, USA. Electronic address: Yaoyao.Pollock@ucsf.edu.
¹² Division of Cancer Epidemiology & Genetics, Metabolic Epidemiology Branch, National Cancer Institute, 9609 Medical Center Dr, Rockville, MD 20850, USA. Electronic address: elizabeth.salerno@nih.gov.
¹³ Department of Medicine, Hematology/Oncology, University of Rochester Medical Center, 601 Elmwood Ave, Box 704, Rochester, NY 14642, USA. Electronic address: Allison_magnuson@urmc.rochester.edu.
¹⁴ Division of Geriatrics, Department of Internal Medicine, University of São Paulo Medical School, Hospital Sírio-Libanês- Geriatric Oncology Team, Av. Dr. Enéas de Carvalho Aguiar, 155, 8° Andar, Bloco 3, São Paulo, SP CEP 05403-900, Brazil.
¹⁵ Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 641 Lexington Ave, New York, NY 10022, USA. Electronic address: ahlest@mskcc.org.

Abstract

Cancer-related cognitive decline (CRCD) may have particularly significant consequences for older adults, impacting their functional and physical abilities, level of independence, ability to make decisions, treatment adherence, overall quality of life, and ultimately survival. In honor of Dr. Hurria's work we explore and examine multiple types of screening, assessment and non-pharmacologic treatments for CRCD. We then suggest future research and clinical practice questions to holistically appreciate the complexity of older adults with cancer's experiences and fully integrate the team-based approach to best serve this population.

Keywords: Assessment; Cancer-related cognitive decline; Older adults; Rehabilitation.

Publication types

Review

MeSH terms

Aged
Cognitive Dysfunction* / etiology
Cognitive Dysfunction* / therapy
Geriatric Assessment
Humans
Mass Screening
Medical Oncology
Neoplasms* / complications
Neoplasms* / therapy
Quality of Life

Abstract

Publication types

MeSH terms

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