Introduction to Protein Nanotechnology

Methods Mol Biol. 2020:2073:1-13. doi: 10.1007/978-1-4939-9869-2_1.

Abstract

Protein nanotechnology research is at the intersection of protein biology and nanotechnology. Protein molecules are repurposed as nanostructures and nanoscaffolds, and nanoscale tools are used to investigate protein assembly and function. In this chapter, a select review is given of some of the recent examples of protein nanostructures, covering both those directly borrowed from biology and those designed for use in nanotechnology. It updates the introductory chapter to Edition 2 of this volume to reflect significant progress in this field. Some strategies to incorporate protein structures into devices are also covered, with the successes and challenges of this interdisciplinary field identified. This provides an overarching framework for the rest of the volume, which details the case studies of some of the protein building blocks that have been designed and produced, along with tips and tools for their incorporation into devices and making functional measurements.

Keywords: Protein nanotechnology; Self-assembly; Supramolecular; Tecton.

MeSH terms

  • Animals
  • Humans
  • Nanotechnology / methods*
  • Proteins / chemistry*

Substances

  • Proteins