Rethinking the impact of RG-I mainly from fruits and vegetables on dietary health

Crit Rev Food Sci Nutr. 2020;60(17):2938-2960. doi: 10.1080/10408398.2019.1672037. Epub 2019 Oct 14.

Abstract

Rhamnogalacturonan I (RG-I) pectin is composed of backbone of repeating disaccharide units →2)-α-L-Rhap-(1→4)-α-D-GalpA-(1→ and neutral sugar side-chains mainly consisting of arabinose and galactose having variable types of linkages. However, since traditional pectin extraction methods damages the RG-I structure, the characteristics and health effects of RG-I remains unclear. Recently, many studies have focused on RG-I, which is often more active than the homogalacturonan (HG) portion of pectic polysaccharides. In food products, RG-I is common to fruits and vegetables and possesses many health benefits. This timely and comprehensive review describes the many different facets of RG-I, including its dietary sources, history, metabolism and potential functionalities, all of which have been compiled to establish a platform for taking full advantage of the functional value of RG-I pectin.

Keywords: Pectin; bioactivity; dietary sources; diseases; gut microbiota fermentation; metabolism of RG-I.

Publication types

  • Review

MeSH terms

  • Diet, Healthy*
  • Fruit / chemistry*
  • Functional Food
  • Humans
  • Pectins / metabolism
  • Pectins / pharmacology*
  • Vegetables / chemistry*

Substances

  • rhamnogalacturonan I
  • Pectins