Segmentation and Diagnosis of Liver Carcinoma Based on Adaptive Scale-Kernel Fuzzy Clustering Model for CT Images

J Med Syst. 2019 Oct 10;43(11):322. doi: 10.1007/s10916-019-1459-2.

Abstract

Medical image analysis plays an important role in computer-aided liver-carcinoma diagnosis. Aiming at the existing image fuzzy clustering segmentation being not suitable to segment CT image with non-uniform background, a fast robust kernel space fuzzy clustering segmentation algorithm is proposed. Firstly, the sample in euclidean space is mapped into the high dimensional feature space through the kernel function. Then the linear weighted filtering image is obtained by combining the current pixel with its neighborhood pixels through the space information in CT image. Finally, the two-dimensional histogram between the clustered pixel and its neighborhood mean is introduced into the robust kernel space image fuzzy clustering, and the iterative expression of the fast robust fuzzy clustering in kernel space is obtained by using Lagrange multiplier method. The experimental results on four databases show that our proposed method can segment liver tumors from abdominal CT volumes effectively and automatically, and the comprehensive segmentation performance of the proposed method is superior to that of several existing methods.

Keywords: European space; Fuzzy clustering; Lagrange multiplier; Linear weighted filtering; Liver carcinoma; Non-uniform background; Scale-kernel space.

MeSH terms

  • Algorithms
  • Diagnosis, Computer-Assisted
  • Fuzzy Logic*
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Liver Neoplasms / diagnostic imaging*
  • Liver Neoplasms / pathology*
  • Tomography, X-Ray Computed / methods*