Molecularly imprinted polypyrrole based electrochemical sensor for selective determination of 4-ethylphenol

Olga Domínguez-Renedo; A Marta Navarro-Cuñado; Victor Arnáiz-Lozano; M Asunción Alonso-Lomillo

doi:10.1016/j.talanta.2019.120351

Molecularly imprinted polypyrrole based electrochemical sensor for selective determination of 4-ethylphenol

Talanta. 2020 Jan 15:207:120351. doi: 10.1016/j.talanta.2019.120351. Epub 2019 Sep 16.

Authors

Olga Domínguez-Renedo¹, A Marta Navarro-Cuñado², Victor Arnáiz-Lozano³, M Asunción Alonso-Lomillo³

Affiliations

¹ Analytical Chemistry Department, Faculty of Sciences, University of Burgos, Pza. Misael Bañuelos s/n, 09001, Burgos, Spain. Electronic address: olgado@ubu.es.
² Physical Chemistry Department, Faculty of Sciences, University of Burgos, Pza. Misael Bañuelos s/n, 09001, Burgos, Spain.
³ Analytical Chemistry Department, Faculty of Sciences, University of Burgos, Pza. Misael Bañuelos s/n, 09001, Burgos, Spain.

PMID: 31594580
DOI: 10.1016/j.talanta.2019.120351

Abstract

This work describes the development of an electrochemical sensor based on a molecularly imprinted polymer (MIP) for sensitive and selective determination of 4-ethylphenol in wine. The sensor has been built by means of the electrosynthesis of the MIP on a glassy carbon electrode surface using cyclic voltammetry. The electropolymerization has been performed in the presence of 4-ethylphenol and pyrrole as template molecule and functional monomer, respectively. The influence of the molar ratios of template molecules to functional pyrrole monomers and the time needed to remove the template have been optimized taking into account the differential pulse voltammetric response of 4-ethylphenol. Under the optimal experimental conditions the developed MIP/GCE sensor shows good capability of detection (0.2 μM, α = β = 0.05) and reproducibility (3.0%) in the concentration range from 0.2 to 34.8 μM. The influence of possible interfering species in the analytical response has been studied and the sensor has successfully been applied to the determination of 4-ethylphenol in different wine samples.

Keywords: 4-ethylphenol; Electrochemical sensor; Molecularly imprinted polymer; Polypyrrole; Wine.