. Protecting Cultural Heritage (CH) from corrosion and other environmental damages, mainly involving metallic or organic layers contained in artwork, represents a major challenge for conservation scientists. Electrochemical techniques provide useful information about the deterioration effects of metallic coatings and organic layers. Recently, Electrochemical Impedance Spectroscopy (EIS) has been successfully applied in the study of metallic corrosion. However, EIS has not succeeded in becoming a routine technique, due to problems regarding both instrumental apparatus (which is not ideal for in situ analysis, especially with previous cell configurations), and the difficulty with data processing. At the same time, new portable electrochemical sensors, immunosensors, and biosensors have successfully made a scientific impact, mainly with in situ diagnosis of organic components contained in CH objects. For this purpose, this review presents two sections: the first describes the analytical optimization of impedance electrochemical cell geometries that are suitable for in situ metal-coating investigation; the second reports on the assembly of small electrochemical sensors, immunosensors, and biosensors, which useful for in situ organic layer characterization. This overview summarizes the state of the art regarding the application of electrochemical techniques and small electrochemical devices as alternative tools for the understanding of CH.
Keywords: biosensors; cultural heritage; electrochemical impedance spectroscopy (EIS); graphene oxide; metallic corrosion; portable immunosensors; screen-printed electrodes (SPEs); small sensors; voltammetric techniques.