hnRNPA2B1: Fueling Antiviral Immunity from the Nucleus

Fiachra Humphries; Katherine A Fitzgerald

doi:10.1016/j.molcel.2019.09.021

hnRNPA2B1: Fueling Antiviral Immunity from the Nucleus

Mol Cell. 2019 Oct 3;76(1):8-10. doi: 10.1016/j.molcel.2019.09.021.

Authors

Fiachra Humphries¹, Katherine A Fitzgerald²

Affiliations

¹ University of Massachusetts Medical School, Worcester, MA 01655, USA.
² University of Massachusetts Medical School, Worcester, MA 01655, USA. Electronic address: kate.fitzgerald@umassmed.edu.

PMID: 31585104
DOI: 10.1016/j.molcel.2019.09.021

Abstract

In a recently published article in Science, Cao and colleagues (Wang et al., 2019) identify hnRNPA2B1 as a new DNA-binding protein that initiates and amplifies antiviral immunity, unveiling a new facet of DNA recognition in the nucleus.

Publication types

Comment

MeSH terms

Antiviral Agents*
Cell Nucleus
DNA Viruses
Heterogeneous-Nuclear Ribonucleoprotein Group A-B*
Immunity, Innate

Substances

Antiviral Agents
Heterogeneous-Nuclear Ribonucleoprotein Group A-B

Grants and funding

R37 AI067497/AI/NIAID NIH HHS/United States