Patterns of phlebotomy blood loss and transfusions in extremely low birth weight infants

J Perinatol. 2019 Dec;39(12):1670-1675. doi: 10.1038/s41372-019-0515-6. Epub 2019 Oct 3.

Abstract

Objective: Characterize frequency and volume of blood draws and transfusions in extremely low birth weight infants in the first 10 weeks of life.

Study design: We included infants with a birth weight <1000 g born 23 0/7-29 6/7 weeks gestational age (GA) and with a length of stay ≥10 weeks, admitted between 2014 and 2016 to a single neonatal intensive care unit.

Results: Of 54 infants, median (25th, 75th percentile) GA and birth weight were 25 weeks (24, 26) and 665 g (587, 822), respectively. Median number of blood draws per infant decreased from 57 (49, 65) in week 1 to 12 (8, 22) in week 10. Median volume of blood extracted was 83 mL (70, 97), and median number of blood transfusions was 8 (5, 10).

Conclusions: This cohort experienced a high number and volume of blood draws. Draw frequency and transfusions decreased over the first 10 weeks of life.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Anemia / etiology*
  • Anemia / therapy
  • Erythrocyte Transfusion / statistics & numerical data*
  • Female
  • Humans
  • Infant, Extremely Low Birth Weight*
  • Infant, Extremely Premature
  • Infant, Newborn
  • Infant, Premature*
  • Infant, Premature, Diseases / etiology*
  • Infant, Premature, Diseases / therapy
  • Intensive Care Units, Neonatal
  • Male
  • Phlebotomy / adverse effects
  • Phlebotomy / statistics & numerical data*