Importance of Translational Research for Targeting Fibroblast Growth Factor Receptor Signaling in Cancer

Klaus Holzmann; Brigitte Marian

doi:10.3390/cells8101191

Importance of Translational Research for Targeting Fibroblast Growth Factor Receptor Signaling in Cancer

Cells. 2019 Oct 2;8(10):1191. doi: 10.3390/cells8101191.

Authors

Klaus Holzmann¹, Brigitte Marian²

Affiliations

¹ Medical University of Vienna, Comprehensive Cancer Center, Department of Medicine I, Division of Cancer Research, Borschkegasse 8a, 1090 Vienna, Austria. klaus.holzmann@meduniwien.ac.at.
² Medical University of Vienna, Comprehensive Cancer Center, Department of Medicine I, Division of Cancer Research, Borschkegasse 8a, 1090 Vienna, Austria. brigitte.marian@meduniwien.ac.at.

Abstract

Fibroblast growth factors (FGFs) are a large family of protein ligands that exert a wide range of biological effects in many organs/tissues by activating receptors (FGFRs) of the tyrosine kinase superfamily [...].

Publication types

Editorial
Introductory Journal Article

MeSH terms

Animals
Cell Line, Tumor
Humans
Molecular Targeted Therapy*
Neoplasms / drug therapy*
Receptors, Fibroblast Growth Factor / antagonists & inhibitors*
Translational Research, Biomedical

Substances

Receptors, Fibroblast Growth Factor