Blind Equalization of Lung Crackle Sounds to Compensate Chest Attenuation

IEEE J Biomed Health Inform. 2020 Jun;24(6):1796-1804. doi: 10.1109/JBHI.2019.2944995. Epub 2019 Oct 1.

Abstract

Diseased lungs generate adventitious sounds that propagate through the thorax, reaching the surface where they may be heard or recorded. The attenuation imposed to the lung sounds by the thorax depends on the physical characteristics of each patient, hampering the analysis of quantitative indexes measured to assist the diagnosis of cardiorespiratory disorders. This work proposes the application of a blind equalizer (eigenvector algorithm - EVA) to reduce the effects of thorax attenuation on indexes measured from crackle sounds. Computer simulated crackles (acquired on the posterior chest wall after being applied to volunteer's mouth) and actual crackles belonging to a database were equalized. Quantitative indexes were measured from crackles before and after equalization. Comparison of indexes measured from simulated crackles reveals that the equalizer improves the results due to attenuation compensation and removal of Gaussian noise. Effects of equalization on indexes measured from actual crackles were qualitatively assessed. Results point out that blind equalization of crackles recorded on the thorax provides more consistent quantitative indexes to assist the diagnosis of different cardiorespiratory diseases.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Diagnosis, Computer-Assisted / methods*
  • Humans
  • Lung / physiopathology
  • Respiratory Sounds / classification*
  • Signal Processing, Computer-Assisted*
  • Sound Spectrography