Pyogranulomatous pleuropneumonia caused by Nocardia asiatica in a dog coinfected with canine morbillivirus (canine distemper virus)

Vet Med Sci. 2020 Feb;6(1):25-31. doi: 10.1002/vms3.202. Epub 2019 Oct 1.

Abstract

Nocardia asiatica causing pyogranulomatous pleuropneumonia is reported for the first time in a dog coinfected with canine morbillivirus (CM), diagnosed based on epidemiological, clinical, haematological, images, microbiological, histopathological, polymerase chain reaction and hsp65 gene sequencing findings. The immunosuppression of CM probably favoured the opportunistic behaviour of N. asiatica. Despite the therapeutic measures, the animal died, mainly due to respiratory distress. The association of methods to improve early diagnosis, therapy procedures and prognosis of canine nocardiosis is discussed, as well as the close relationship between pets and their owners, which may favour the transmission of pathogens such as Nocardia from pets-to-humans, which poses an emerging public health issue.

Keywords: actinomycetes; canine nocardiosis; combined infection; hsp65; sequencing.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Brazil
  • Coinfection / diagnostic imaging
  • Coinfection / veterinary*
  • Distemper / complications*
  • Distemper / diagnostic imaging
  • Distemper Virus, Canine / isolation & purification*
  • Dogs
  • Fatal Outcome
  • Female
  • Nocardia / isolation & purification*
  • Nocardia Infections / complications
  • Nocardia Infections / diagnosis
  • Nocardia Infections / veterinary*
  • Pleuropneumonia / complications
  • Pleuropneumonia / diagnostic imaging
  • Pleuropneumonia / veterinary*

Supplementary concepts

  • Nocardia asiatica