BRAF exon 11 mutant melanoma and sensitivity to BRAF/MEK inhibition: Two case reports

MeSH terms

• Adult
• Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
• Drug Resistance, Neoplasm / genetics*
• Exons / genetics
• Female
• Humans
• Imidazoles / administration & dosage*
• MAP Kinase Kinase Kinases / antagonists & inhibitors
• Male
• Melanoma / drug therapy*
• Melanoma / genetics
• Melanoma / pathology
• Middle Aged
• Mutation
• Neoplasm Metastasis
• Oximes / administration & dosage*
• Protein Kinase Inhibitors / administration & dosage
• Proto-Oncogene Proteins B-raf / antagonists & inhibitors
• Proto-Oncogene Proteins B-raf / genetics*
• Pyridones / administration & dosage*
• Pyrimidinones / administration & dosage*
• Skin Neoplasms / drug therapy*
• Skin Neoplasms / genetics
• Skin Neoplasms / pathology
• Treatment Outcome