We describe how a long-range repulsive interaction can surreptitiously modify the effective geometry of approaching compliant surfaces, with significant consequences on friction. We investigated the behavior under shear and compression of mica surfaces coated with poly(N-isopropylacrylamide) pNIPAM-based cationic microgels. We show that local surface deformations as small as a few nanometers must be considered to understand the response of such surfaces under compression and shear, in particular when the range of action of normal and friction forces are significantly different, as is often the case for macromolecular lubrication. Under these conditions, a subtle interplay between normal forces and surface compliance may significantly reduce friction increment by limiting the minimum approach of the surfaces under pressure. We found that stiffening of compressed microgels confined in the region of closest approach make it increasingly difficult to reduce the gap between the mica surfaces, limiting the deformation of microgels distant from the contact apex and their contribution to global friction while increasing the effective contact radius. These findings reveal a simple mechanism for a robust control of lubrication: by properly tuning the stiffness and geometry of the interacting bodies, for an ad hoc long-range interaction, the growth of friction with applied normal load can be significantly hindered. Thus, substrate compliance is as significant as surface interaction in the design of low friction, long life tribological systems.