Factors affecting outcomes after supermicrosurgical lymphovenous anastomosis in a defined patient population

Clin Hemorheol Microcirc. 2019;73(1):53-63. doi: 10.3233/CH-199213.

Abstract

Background: The optimal surgical treatment for lymphedema is still subject of intensive research. Therefore, it is vital to investigate what significance lymphovenous anastomosis (LVA) has in this context.

Objective: This study aims to determine the short- and long-term results as well as the most important factors that can improve outcomes after LVA.

Methods: This study includes a complete data set of 26 patients who received LVA for a therapy-resistant lymphedema. Patients were followed up for an average of 23 months.

Results: 50% of the patients reported a subjective improvement. Without conservative treatment after the operation the patients showed significant better results (100% vs. 40.9%, p = 0.030). The localization of lymphedema as well as the region of LVA had a significant influence. In patients with lymphedema affecting the entire leg, symptom improvement was significantly lower (35.3% vs. 77.8%, p = 0.039). Patients who received LVA in an upper limb show a significantly higher improvement in symptoms than patients who received LVA in a lower limb (100% vs. 30%, p = 0.021).

Conclusions: We identified factors with a significant influence on the outcome of patients after receiving LVA. Patients with early-stage upper extremity lymphedema seem to benefit most from this procedure.

Keywords: Lymphedema surgery; lymphovenous anastomosis; microsurgery; postoperative care; results.

MeSH terms

  • Adult
  • Aged
  • Anastomosis, Surgical / methods*
  • Female
  • Humans
  • Lymphatic Vessels / physiopathology*
  • Male
  • Middle Aged
  • Treatment Outcome
  • Vascular Surgical Procedures / methods*