Low Dose of Dipotassium Glycyrrhizate Counteracts Atherosclerosis Progression in Apoe-/- Female Mice

J Vasc Res. 2019;56(5):267-270. doi: 10.1159/000502692. Epub 2019 Sep 24.

Authors

Francesca Palone¹, Emanuela Pasquali², Paola Giardullo³, Laura Stronati⁴, Roberta Vitali², Mariateresa Mancuso⁵

Affiliations

¹ Pediatric Gastroenterology and Liver Unit, Department of Pediatrics, Sapienza University of Rome, Rome, Italy.
² Laboratory of Biomedical Technologies, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, ENEA, Rome, Italy.
³ Department of Radiation Physics, Guglielmo Marconi University, Rome, Italy.
⁴ Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.
⁵ Laboratory of Biomedical Technologies, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, ENEA, Rome, Italy, mariateresa.mancuso@enea.it.

PMID: 31550706
DOI: 10.1159/000502692

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Aorta, Thoracic / drug effects*
Aorta, Thoracic / metabolism
Aorta, Thoracic / pathology
Aortic Diseases / etiology
Aortic Diseases / metabolism
Aortic Diseases / pathology
Aortic Diseases / prevention & control*
Atherosclerosis / etiology
Atherosclerosis / metabolism
Atherosclerosis / pathology
Atherosclerosis / prevention & control*
Disease Models, Animal
Disease Progression
Female
Glycyrrhizic Acid / pharmacology*
HMGB1 Protein / metabolism
Inflammation Mediators / metabolism
Lipids / blood
Mice, Knockout, ApoE
Plaque, Atherosclerotic
Sex Factors

Substances

HMGB1 Protein
HMGB1 protein, mouse
Inflammation Mediators
Lipids
Glycyrrhizic Acid