Antimicrobial peptides with protease stability: progress and perspective

Changxuan Shao; Yongjie Zhu; Zhenheng Lai; Peng Tan; Anshan Shan

doi:10.4155/fmc-2019-0167

Antimicrobial peptides with protease stability: progress and perspective

Future Med Chem. 2019 Aug;11(16):2047-2050. doi: 10.4155/fmc-2019-0167.

Authors

Changxuan Shao¹, Yongjie Zhu¹, Zhenheng Lai¹, Peng Tan¹, Anshan Shan¹

Affiliation

¹ Laboratory of Molecular Nutrition and Immunity, Institute of Animal Nutrition, Northeast Agricultural University, Harbin, PR China.

PMID: 31538527
DOI: 10.4155/fmc-2019-0167

No abstract available

Keywords: PEGylation; antimicrobial peptides; appropriate formulation; chemical modification; de novo design; lipopeptide; peptidomimetic; prodrug; protease stability; unnatural amino acid.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acids / chemistry
Animals
Anti-Infective Agents / chemistry*
Antimicrobial Cationic Peptides / chemistry*
Drug Design*
Drug Stability
Humans
Peptide Hydrolases / chemistry
Peptidomimetics / chemistry
Polyethylene Glycols / chemistry
Prodrugs / chemistry
Protein Stability
Proteolysis

Substances

Amino Acids
Anti-Infective Agents
Antimicrobial Cationic Peptides
Peptidomimetics
Prodrugs
Polyethylene Glycols
Peptide Hydrolases