Marijuana use and outcomes in adult and pediatric trauma patients after legalization in California

Am J Surg. 2019 Dec;218(6):1189-1194. doi: 10.1016/j.amjsurg.2019.08.020. Epub 2019 Sep 10.

Abstract

Background: Marijuana has become legal in eight states since 2012. We hypothesized the incidence of marijuana-positive trauma patients and rate of mortality has increased post-legalization.

Methods: A single level-I trauma center was used to identify patients screening positive for marijuana on urine-toxicology. Patients in the pre-legalization and post-legalization periods were compared.

Results: In the pre-legalization cohort 9.4% were marijuana-positive versus 11.0% in the post-legalization cohort (p = 0.001). Marijuana-positive patients post-legalization had higher rates of critical trauma activation (20.0% vs. 15.0%, p = 0.01) and mortality (2.6% vs. 1.2%, p = 0.03). In the pediatric (age 12-17) subgroup, the incidence of marijuana-positive patients did not change after legalization (pre: 39.3%, post: 46.4%, p = 0.24).

Conclusion: The incidence of marijuana-positive trauma patients increased post-legalization. Adult marijuana-positive trauma patients post-legalization were more likely to meet criteria for critical trauma activation and have a higher mortality rate. A subgroup of pediatric patients had an alarmingly high rate of marijuana use.

Summary: The rate of marijuana use among trauma patients increased post-legalization in California. The rate of critical trauma activation also increased as well as the mortality rate.

Keywords: California; Marijuana; Mortality; Post-legalization; Trauma.

MeSH terms

  • Adolescent
  • Adult
  • California / epidemiology
  • Child
  • Female
  • Humans
  • Incidence
  • Male
  • Marijuana Use / epidemiology*
  • Marijuana Use / legislation & jurisprudence*
  • Registries
  • Substance-Related Disorders / epidemiology
  • Trauma Centers
  • Wounds and Injuries / epidemiology*
  • Wounds and Injuries / surgery*