Loop-mediated isothermal amplification (LAMP): Expansion of its practical application as a tool to achieve universal health coverage

Yasuyoshi Mori; Tsugunori Notomi

doi:10.1016/j.jiac.2019.07.020

Loop-mediated isothermal amplification (LAMP): Expansion of its practical application as a tool to achieve universal health coverage

J Infect Chemother. 2020 Jan;26(1):13-17. doi: 10.1016/j.jiac.2019.07.020. Epub 2019 Sep 10.

Authors

Yasuyoshi Mori¹, Tsugunori Notomi²

Affiliations

¹ Eiken Chemical Co.,Ltd, Biochemical Research Laboratory II, Research and Development Division, Japan. Electronic address: yasuyoshi_mori@eiken.co.jp.
² Eiken Chemical Co.,Ltd, Research and Development Division, Japan.

PMID: 31519395
DOI: 10.1016/j.jiac.2019.07.020

Abstract

Since its invention in 2000, loop-mediated isothermal amplification (LAMP) has attracted great interest from researchers and has been used as a simple and rapid diagnostic tool for detection of infectious and non-infectious diseases. Here we review the recent circumstances and outcomes of these applications of LAMP to show the potential of LAMP as a tool for achieving universal health coverage (UHC). A future application of LAMP, such as in an automated multiplex format, is also discussed.

Keywords: Cancer; Infectious diseases; LAMP; PURE; Universal health coverage.

Publication types

Review

MeSH terms

Communicable Diseases / diagnosis
Humans
Molecular Diagnostic Techniques*
Neoplasms / diagnosis
Nucleic Acid Amplification Techniques*
Universal Health Insurance*