Clinical Utilization of Pharmacogenetics in Psychiatry - Perspectives of Pharmacists, Genetic Counselors, Implementation Science, Clinicians, and Industry

Pharmacopsychiatry. 2020 Jul;53(4):162-173. doi: 10.1055/a-0975-9595. Epub 2019 Sep 11.

Abstract

Introduction: The use of pharmacogenomic (PGx) testing to guide decisions and improve patient outcomes has increased in recent years. PGx testing represents a decision support tool that may inform dosing, increase the likelihood of treatment response, and identify patients at risk for medication side effects.

Methods: This is a narrative review of utilization of PGx testing in psychiatry from stakeholders including, pharmacists, genetic counselors, implementation scientists, industry, and clinicians.

Results: While many limitations exist to streamline use of PGx testing in psychiatry, various stakeholders are crucial to clinical implementation.

Discussion: PGx testing can assist in medication selection and improve patient outcomes; however, more data are needed to understand when and how to incorporate PGx testing into psychiatric practice.

Publication types

  • Review

MeSH terms

  • Genetic Counseling
  • Genetic Testing
  • Health Care Sector
  • Humans
  • Implementation Science
  • Pharmacists
  • Pharmacogenetics*
  • Psychiatry / methods*